SCN1A mutations are the main cause of the epilepsy disorders Dravet syndrome (DS) and genetic epilepsy with febrile seizures plus (GEFS+).Mutations that reduce the activity of the mouse Scn8a gene, in contrast, are found to confer seizure resistance and extend the lifespan of mouse models of DS and GEFS+.To investigate the mechanism by which reduce
The work is devoted to the study of the complementarity of the electronic structures of the ligands and SARS-CoV-2 RNA-dependent RNA polymerase.The research methodology was based on determining of 3D maps of electron densities of complexes Nuts using an original quantum free-orbital AlteQ approach.We observed a positive relationship between the par
This paper uses the qualitative unstructured interviews and Focus Group Discussions (FGD) to understand how Bamasaaba men conceptualise masculinity in response to safe medical male circumcision (SMMC) in Ugandan.Results were obtained from cultural leaders, clan leaders, Nuts traditional surgeons, medical officers, 2016 initiates, focus groups and t
In November 2022, ChatGPT 3.5 was 9RG released on a public research preview, gaining notoriety for its ability to pull from a vast body of information to create coherent and digestible bodies of text that accurately respond to queries (OpenAI, 2022).It is able to recognise the grammar and vocabulary of ancient languages, translate passages, and com